BASE

What is BASE?

BASE is a rinsing solution able to remove antibiotics from various human tissues intended for transplantation (cardiovascular, musculoskeletal, osteotendons, skin and amniotic membrane) after decontamination.

The solution also removes the DMSO residues from tissues after cryopreservation and preserves the integrity of the tissue, due to the proprietary formula based on RPMI 1640.

The BASE rinsing solution can also be used for tissue transport to the bank or during tissue dissection.

Intended use

RINSING AND TRANSPORT OF HUMAN TISSUES (CARDIOVASCULAR, MUSCULOSKELETAL, OSTEOTENDONS, SKIN AND AMNIOTIC MEMBRANE)

Characteristics

STERILE
PYROGEN-FREE
MYCOPLASMA-FREE
CE MARK: 0477

Technical Documents

CE Certificate 335.83 KB 2369 downloads

AL.CHI.MI.A. S.R.L. production quality system is compliant with Annex Il (excluding...

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Technical Sheet - BAS 007-00 461.30 KB 191 downloads

BASE - 500 ml ...

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Surgical Videos

BASE – Rinsing of tissue processed

Publications and Presentations

Logistics of an advanced therapy medicinal product during COVID-19 pandemic in Italy: successful delivery of mesenchymal stromal cells in dry ice
Year: 2020 Authors: Astori G.; Bernardi M.; Bozza A.; Catanzaro D.; Chieregato K.; Merlo A.; Santimaria M.; Barbazza R.; Amodeo G.; Ciccocioppo R.; Elice F.; Ruggeri M. J Transl Med 18, 451 (2020) doi.org/10.1186/s12967-020-02625-0 Online version This is a: Publication [...]
Establishing a procedure for dimethyl sulfoxide removal from cardiovascular allografts: a quantitative study
Year: 2013 Authors: Gatto C.; Dainese L.; Buzzi M.; Terzi A.; Guarino A.; Pagliaro P.P.; Polvani G.; D’Amato Tothova J. Cell and Tissue Banking 14(2): 205-12, 2013 Online version This [...]
A suitable and efficient procedure for the removal of decontaminating antibiotics from tissue allografts
Year: 2013 Authors: Gatto C.; Giurgola L.; D’Amato Tóthová J. Cell and Tissue Banking 14(1), 107-115, 2013 Online version This is a: Publication Abstract: The presence of residual antibiotics [...]
Establishment of a rinsing procedure to eliminate antibiotic and glycerol residues from cryopreserved skin decontaminated with BASE.128
Year 2011, EATB Authors: Pianigiani E.; Gatto C.; Giurgola L.; D’Amato Tóthová, J. Abstract: Skin decontamination and cryopreservation can result in the presence of antibiotic and glycerol residues, which shall be removed before transplantation [...]
Optimization of cardiovascular tissue decontamination and rinsing with BASE.128 and BASE
Year: 2011, EATB Authors: Terzi A.; Buzzi M.; Guarino A.; Dainese L.; Vasuri F., D’Amato Tóthová J.; Gatto C. Abstract: We studied the optimal conditions to decontaminate and rinse cardiovascular tissues intended for transplantation [...]
Removal of Me2SO from cryopreserved skin and heart valves CRYO 2010
Year: 2010, CRYO Authors: Gatto C.; Marchiani A.; Ruzza P.; Beccaro M.; D’Amato Tóthová J. Abstract: Elimination of Me2SO from cryopreserved allografts is one of the crucial steps in tissue processing phases in order to [...]
Elimination of antibiotic carry-over from tissues decontaminated with Base.128
Year: 2010, EATB Authors: Gatto C.; Beccaro M.; Lipartiti M.; D’Amato Tóthová J. Abstract: Decontamination of tissue allografts in antibiotic cocktails can lead to the antibiotic carry-over effect, which in turn can result in [...]
Removal of DMSO from cryopreserved human skin
Year: 2010, EATB Authors: Vassanelli A.; Gatto C.; Bosinelli A.; Rizzi S.; Marchiani A.; Ruzza P.; D’Amato Tóthová J.; Aprili G. Abstract: Elimination of DMSO from cryopreserved skin allografts is one of the crucial [...]
Removal of DMSO from cardiovascular allografts
Year: 2010, EATB Authors: Guarino A.; Gatto C.; Dainese L.; Buzzi M.; Pagliaro P.; D’Amato Tóthová J.; Polvani G.L. Abstract: Elimination of DMSO from cryopreserved allografts is one of the crucial steps in tissue processing [...]
Comparison among the medical devices BASE.128, BASE, CRYO.ON and the solutions currently used in two Italian cardiovascular tissue banks
Year: 2010, EATB Authors: Gatto C.; Marchiani A.; Ruzza P.; Beccaro M.; D’Amato Tóthová, J. Abstract: We evaluated the performances of the HTP medical devices in comparison with solutions currently used by the Cardiovascular Tissue [...]

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Details

BASE 128

Packaging: Bottle
Items: 1
Volume: 250 ml, 500 ml

BASE•128 is a ready-to-use solution to decontaminate various human tissues intended for transplantation (cardiovascular,
musculoskeletal, osteotendons, skin and amniotic membrane) in di [...]
Category: DecontaminationTissue banking

What is BASE?

Intended use

Characteristics

Technical Documents

CE Certificate 335.83 KB 2369 downloads

Technical Sheet - BAS 007-00 461.30 KB 191 downloads

Surgical Videos

Publications and Presentations

Logistics of an advanced therapy medicinal product during COVID-19 pandemic in Italy: successful delivery of mesenchymal stromal cells in dry ice

Establishing a procedure for dimethyl sulfoxide removal from cardiovascular allografts: a quantitative study

A suitable and efficient procedure for the removal of decontaminating antibiotics from tissue allografts

Establishment of a rinsing procedure to eliminate antibiotic and glycerol residues from cryopreserved skin decontaminated with BASE.128

Optimization of cardiovascular tissue decontamination and rinsing with BASE.128 and BASE

Removal of Me2SO from cryopreserved skin and heart valves CRYO 2010

Elimination of antibiotic carry-over from tissues decontaminated with Base.128

Removal of DMSO from cryopreserved human skin

Removal of DMSO from cardiovascular allografts

Comparison among the medical devices BASE.128, BASE, CRYO.ON and the solutions currently used in two Italian cardiovascular tissue banks

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