BASE 128

¿Qué es BASE.128?

BASE•128 es una solución lista para la descontaminación de diversos tejidos humanos destinados al trasplante (cardiovascular, musculoesquelético, osteotendineo, piel y membrana amniótica) en diferentes condiciones de tiempo y temperatura.

La mezcla de los cuatro antibióticos (vancomicina, gentamicina, cefotaxima y desoxicolato de anfotericina B) es activa frente a los contaminantes más frecuentemente detectados en los bancos de tejidos (bacilos Gram positivos y Gram negativos, mohos y levaduras).

La solución descontaminante BASE•128 también puede utilizarse durante el transporte del tejido desde el centro de extracción hasta el banco o durante la disección.

Uso previsto

DESCONTAMINATION DE DIVERSOS TEJIDOS HUMANOS DESTINADOS AL TRASPLANTE (CARDIOVASCULAR, MUSCULOESQUELÉTICO, OSTEOTENDINEO, PIEL Y MEMBRANA AMNIÓTICA)

Características

ESTÉRIL
APIRÓGENO
SIN MYCOPLASMA
MARCA CE: 0477

Documentos Técnicos

Certificado CE 335.83 KB 501 downloads

AL.CHI.MI.A. S.R.L. production quality system is compliant with Annex Il (excluding...

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Ficha Técnica - BAS 005-00 491.61 KB 133 downloads

BASE•128 - 250 ml ...

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Ficha Técnica - BAS 006-00 485.01 KB 132 downloads

BASE•128 - 500 ml ...

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Publicaciones y Presentaciones

Logistics of an advanced therapy medicinal product during COVID-19 pandemic in Italy: successful delivery of mesenchymal stromal cells in dry ice
Año: 2020Autores: Astori G.; Bernardi M.; Bozza A.; Catanzaro D.; Chieregato K.; Merlo A.; Santimaria M.; Barbazza R.; Amodeo G.; Ciccocioppo R.; Elice F.; Ruggeri M. J Transl Med 18, 451 (2020)doi.org/10.1186/s12967-020-02625-0Online version Esta es una: Publicación Abstract Serious intraocular [...]
Strategies for tissue decontamination during umbical cord-derived mesenchymal stromal cells production and determination of antibiotic residues final product
Año: 2019, European Association of Tissue and Cell Banks (EATCB) Autores: Chieregato K.; Gatto C.; Alghisi A.; Bianchini G.; Bernardi M.; Bozza A.; Catanzaro D.; Giurgola L.; Lievore C.; Mozzo V.; Perbellini O.; Rassu [...]
Production of umbical cord-derived Mesenchymal stromal cells in an hospital based-GMP facility: from tissue collection to ATMP release
Año: 2019, European Association of Tissue and Cell Banks (EATCB) Autores: Chieregato K.; Alghisi A.; Bernardi M.; Bianchini G.; Bozza A.; Catanzaro D.; Lievore C.; Mozzo V.; Perbellini O.; Rassu M.; Ruggeri M.; Tagliaferri [...]
Sterility testing of tissue samples according to European Pharmacopoeia
Año: 2017, EATB Autores: Giurgola L.; Gatto C.; Molena S.; D’Amato Tóthová J. Purpose: The aim of this study was to validate the sterility testing of tissue samples according to the “Method suitability [...]
Decontamination of human larynx with medical device Base.128
Año: 2015, EATB Autores: Carvalho C.; Giurgola L.; Bartley H.; Proctor T.; Gatto C.; D’Amato Tóthová J.; Lowdell M. Background: The aim of the study was to investigate the decontamination of human donor larynx [...]
Decontamination of umbilical cord tissue with Base.128, Time-kill Studies
Año: 2015, EATB Autores: Giurgola L.; Gatto C.; Cabrita G.; Formosinho P.; D’Amato Tóthová J. Background: Decontamination of umbilical cord is a critical phase before cryopreservation. We investigated the decontamination efficacy of the [...]
Residual antibiotics in decontaminated human cardiovascular tissues intended for transplantation and risk of falsely negative microbiological analyses
Año: 2014 Autores: Buzzi M.; Guarino A.; Gatto C.; Manara S.; Dainese L.; Polvani G.; D’Amato Tóthová J. PLoS One. 2014 Nov 14;9(11):e112679. doi: 10.1371/journal.pone.0112679. eCollection 2014 Online version Esta [...]
Validation of “ResEP tube” system for microbiological analysis with removal of antibiotic residues
Año: 2013, EATB Autores: Giurgola L.; Gatto C.; D’Amato Tóthová J. Abstract: Residual antibiotic concentrations may induce bacteriostasis of microorganisms eventually present on tissue samples and lead to false negative results during microbiological analysis [...]
Validation of a device for elimination of antibiotics from liquid samples undergoing microbiological analysis
Año: 2013, BATB Autores: Giurgola L.; Gatto C.; Vassanelli A.; Guarino A.; Buzzi M.; D’Amato Tóthová J. Abstract: Our previous studies indicated that the use of antibiotic cocktails during tissue processing can lead to an [...]
Evaluation of different microbiological testing methods in tissue banking
Año: 2013, EATB Autores: D’Amato Tóthová J.; Giurgola L.; Gatto C. Abstract: Each tissue bank validates its own method for microbiological analysis of tissues, which is essential to determine whether they can be [...]
A suitable and efficient procedure for the removal of decontaminating antibiotics from tissue allografts
Año: 2013Autores: Gatto C.; Giurgola L.; D’Amato Tóthová J. Cell and Tissue Banking 14(1), 107-115, 2013 Online version Esta es una: Publicación Abstract: The presence of residual antibiotics in tissue [...]
Impact of antibiotic residues on microbiological analysis: implication of tissue banking
Año: 2011, EATB Autores: Gatto C.; Giurgola L.; Beccaro M.; Lipartiti M.; D’Amato Tóthová, J. Abstract: Decontamination of tissue allografts in antibiotic cocktails can lead to an antibiotic carry-over effect, which in turn can result [...]
Establishment of a rinsing procedure to eliminate antibiotic and glycerol residues from cryopreserved skin decontaminated with BASE.128
Año: 2011, EATB Autores: Pianigiani E.; Gatto C.; Giurgola L.; D’Amato Tóthová, J. Abstract: Skin decontamination and cryopreservation can result in the presence of antibiotic and glycerol residues, which shall be removed before [...]
Time-Kill studies of BASE.128 against S. Epidermidis II, S. Capitis and P. Acnes isolated from donor skin
Año: 2011, EATB Autores: Gatto C.; Pianigiani E.; Ierardi F.; Giurgola L.; D’Amato Tóthová, J. Abstract: We investigated the decontamination efficacy of BASE.128 against clinical isolates of the most frequent skin allograft contaminants. Our results [...]
Skin decontamination and impact of antibiotic residues on microbiological tests
Año: 2011, EATB Autores: Vassanelli A.; Bosinelli A.; Rizzi S.; Lucchini E.; Gatto C.; Giurgola L.; D’Amato Tóthová, J. Abstract: The performance of BASE.128 were compared to that of the antibiotic solution currently used [...]
Optimization of cardiovascular tissue decontamination and rinsing with BASE.128 and BASE
Año: 2011, EATB Autores: Terzi A.; Buzzi M.; Guarino A.; Dainese L.; Vasuri F., D’Amato Tóthová J.; Gatto C. Abstract: We studied the optimal conditions to decontaminate and rinse cardiovascular tissues intended for transplantation [...]
Validation of standardized industrial antibiotic cocktails
Año: 2010, Cardiovascular Tissue Bank Meeting Autores: Gatto C.; Giurgola L.; D’Amato Tóthová J. Abstract: The aim of the present study was to evaluate the performances of the industrial antibiotic cocktail BASE.128 as compared [...]
Elimination of antibiotic carry-over from tissues decontaminated with Base.128
Año: 2010, EATB Autores: Gatto C.; Beccaro M.; Lipartiti M.; D’Amato Tóthová J. Abstract: Decontamination of tissue allografts in antibiotic cocktails can lead to the antibiotic carry-over effect, which in turn can result in [...]
Fate of antibiotics after tissue decontamination. Study on heart valves, pericardium, bone and skin
Año: 2010, BATB Autores: D’Amato Tóthová J.; Gatto C.; Cavallaro D.; Beccaro M.; Lipartiti M. Abstract: Elimination of residual antibiotics from allograft/human tissues intended for transplantation after decontamination is paramount to ensure tissue quality and [...]
Effects of tissue, time and temperature on decontamination efficacy of Base.128
Año: 2010, BATB Autores: D’Amato Tóthová J.; Gatto C.; Beccaro M.; Candeo L.; Bortoluzzi S.; Lipartiti M. Introduction: Decontamination is a crucial step in allograft processing. Tissue banks have established their own decontamination [...]
Comparison among the medical devices BASE.128, BASE, CRYO.ON and the solutions currently used in two Italian cardiovascular tissue banks
Año: 2010, EATB Autores: Gatto C.; Marchiani A.; Ruzza P.; Beccaro M.; D’Amato Tóthová, J. Abstract: We evaluated the performances of the HTP medical devices in comparison with solutions currently used by the Cardiovascular [...]
Fate of antibiotics after the tissue decontamination phase: Study on pig heart valves
Año: 2009, EATB Autores: D’Amato Tóthová J.; Gatto C.; Cavallaro D.; Beccaro M.; Lipartiti M. Abstract: Elimination of residual antibiotics from allograft/human tissues intended for transplantation after decontamination is paramount to ensure tissue quality [...]
Effects of temperature on decontamination efficacy of BASE.128 by in vitro Time-Kill studies
Año: 2009, EATB Autores: D’Amato Tóthová J.; Gatto C.; Beccaro M.; Candeo L.; Bortoluzzi S.; Lipartiti M. Abstract: Decontamination is a crucial step in allograft processing. Tissue banks have established decontamination procedures using different [...]

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BASE

BASE es una solución de lavado capaz de eliminar los antibióticos de diferentes tejidos de origen humano destinados al trasplante (cardiovascular, musculoesquelético, osteotendineo, piel y me [...]
Category: Bancos de tejidosLavado de tejidos para trasplante

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Información adicional

Packaging	Botella
Items	1
Volume	250 ml, 500 ml

¿Qué es BASE.128?

Uso previsto

Características

Documentos Técnicos

Certificado CE 335.83 KB 501 downloads

Ficha Técnica - BAS 005-00 491.61 KB 133 downloads

Ficha Técnica - BAS 006-00 485.01 KB 132 downloads

Publicaciones y Presentaciones

Productos relacionados

Solicitar información sobre BASE.128

Solicitar información sobre BASE.128

Información adicional

Productos relacionados

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Ophthalmic Surgery

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