BASE 128

Cos’è BASE.128?

BASE•128 è una soluzione pronta all’uso decontaminare vari tipi di tessuti umani destinati al trapianto (cardiovascolare, muscoloscheletrico, osteotendineo, cute e membrana amniotica) in diverse condizioni di tempo e temperatura.

La miscela di quattro antibiotici (vancomicina, gentamicina, cefotaxime e amfotericina B deossicolato) è attiva contro i contaminanti riscontrati con maggiore frequenza nelle banche dei tessuti (batteri Gram positivi e Gram negativi, muffe e lieviti).

La soluzione decontaminante BASE•128 può essere usata anche durante il trasporto del tessuto dal centro di prelievo alla banca o durante la dissezione.

Destinazione d’uso

DECONTAMINAZIONE DI VARI TESSUTI UMANI DESTINATI AL TRAPIANTO (CARDIOVASCOLARE, MUSCOLOSCHELETRICO, OSTEOTENDINEO, CUTE E MEMBRANA AMNIOTICA)

Caratteristiche

STERILE
APIROGENO
SENZA MICOPLASMI
MARCHIO CE: 0477

Documenti tecnici

Certificato CE 335.83 KB 1059 downloads

AL.CHI.MI.A. S.R.L. è in possesso di un sistema qualità per la garanzia della produzione...

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Documento Tecnico - BAS 005-00 493.39 KB 274 downloads

BASE•128 - 250 ml ...

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Documento Tecnico - BAS 006-00 485.45 KB 242 downloads

BASE•128 - 500 ml ...

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Pubblicazioni e presentazioni

Logistics of an advanced therapy medicinal product during COVID-19 pandemic in Italy: successful delivery of mesenchymal stromal cells in dry ice
Anno: 2020 Autori: Astori G.; Bernardi M.; Bozza A.; Catanzaro D.; Chieregato K.; Merlo A.; Santimaria M.; Barbazza R.; Amodeo G.; Ciccocioppo R.; Elice F.; Ruggeri M. J Transl Med 18, 451 (2020) doi.org/10.1186/s12967-020-02625-0 Online version Questa è una: Pubblicazione [...]
Strategies for tissue decontamination during umbical cord-derived mesenchymal stromal cells production and determination of antibiotic residues final product
Anno: 2019, European Association of Tissue and Cell Banks (EATCB) Autori: Chieregato K.; Gatto C.; Alghisi A.; Bianchini G.; Bernardi M.; Bozza A.; Catanzaro D.; Giurgola L.; Lievore C.; Mozzo V.; Perbellini O.; Rassu [...]
Production of umbical cord-derived Mesenchymal stromal cells in an hospital based-GMP facility: from tissue collection to ATMP release
Anno: 2019, European Association of Tissue and Cell Banks (EATCB) Autori: Chieregato K.; Alghisi A.; Bernardi M.; Bianchini G.; Bozza A.; Catanzaro D.; Lievore C.; Mozzo V.; Perbellini O.; Rassu M.; Ruggeri M.; Tagliaferri [...]
Sterility testing of tissue samples according to European Pharmacopoeia
Anno: 2017, EATB Autori: Giurgola L.; Gatto C.; Molena S.; D’Amato Tóthová J. Purpose: The aim of this study was to validate the sterility testing of tissue samples according to the “Method suitability [...]
Decontamination of human larynx with medical device Base.128
Anno: 2015, EATB Autori: Carvalho C.; Giurgola L.; Bartley H.; Proctor T.; Gatto C.; D’Amato Tóthová J.; Lowdell M. Background: The aim of the study was to investigate the decontamination of human donor larynx [...]
Decontamination of umbilical cord tissue with Base.128, Time-kill Studies
Anno: 2015, EATB Autori: Giurgola L.; Gatto C.; Cabrita G.; Formosinho P.; D’Amato Tóthová J. Background: Decontamination of umbilical cord is a critical phase before cryopreservation. We investigated the decontamination efficacy of the [...]
Residual antibiotics in decontaminated human cardiovascular tissues intended for transplantation and risk of falsely negative microbiological analyses
Anno: 2014 Autori: Buzzi M.; Guarino A.; Gatto C.; Manara S.; Dainese L.; Polvani G.; D’Amato Tóthová J. PLoS One. 2014 Nov 14;9(11):e112679. doi: 10.1371/journal.pone.0112679. eCollection 2014 Online version [...]
Validation of “ResEP tube” system for microbiological analysis with removal of antibiotic residues
Anno: 2013, EATB Autori: Giurgola L.; Gatto C.; D’Amato Tóthová J. Abstract: Residual antibiotic concentrations may induce bacteriostasis of microorganisms eventually present on tissue samples and lead to false negative results during microbiological analysis [...]
Validation of a device for elimination of antibiotics from liquid samples undergoing microbiological analysis
Anno: 2013, BATB Autori: Giurgola L.; Gatto C.; Vassanelli A.; Guarino A.; Buzzi M.; D’Amato Tóthová J. Abstract: Our previous studies indicated that the use of antibiotic cocktails during tissue processing can lead to an [...]
Evaluation of different microbiological testing methods in tissue banking
Anno: 2013, EATB Autori: D’Amato Tóthová J.; Giurgola L.; Gatto C. Abstract: Each tissue bank validates its own method for microbiological analysis of tissues, which is essential to determine whether they can be released [...]
A suitable and efficient procedure for the removal of decontaminating antibiotics from tissue allografts
Anno: 2013 Autori: Gatto C.; Giurgola L.; D’Amato Tóthová J. Cell and Tissue Banking 14(1), 107-115, 2013 Online version Questa è una: Pubblicazione Abstract: The presence of residual [...]
Impact of antibiotic residues on microbiological analysis: implication of tissue banking
Anno: 2011, EATB Autori: Gatto C.; Giurgola L.; Beccaro M.; Lipartiti M.; D’Amato Tóthová, J. Abstract: Decontamination of tissue allografts in antibiotic cocktails can lead to an antibiotic carry-over effect, which in turn can result [...]
Establishment of a rinsing procedure to eliminate antibiotic and glycerol residues from cryopreserved skin decontaminated with BASE.128
Anno: 2011, EATB Autori: Pianigiani E.; Gatto C.; Giurgola L.; D’Amato Tóthová, J. Abstract: Skin decontamination and cryopreservation can result in the presence of antibiotic and glycerol residues, which shall be removed before transplantation [...]
Time-Kill studies of BASE.128 against S. Epidermidis II, S. Capitis and P. Acnes isolated from donor skin
Anno: 2011, EATB Autori: Gatto C.; Pianigiani E.; Ierardi F.; Giurgola L.; D’Amato Tóthová, J. Abstract: We investigated the decontamination efficacy of BASE.128 against clinical isolates of the most frequent skin allograft contaminants. Our results [...]
Skin decontamination and impact of antibiotic residues on microbiological tests
Anno: 2011, EATB Autori: Vassanelli A.; Bosinelli A.; Rizzi S.; Lucchini E.; Gatto C.; Giurgola L.; D’Amato Tóthová, J. Abstract: The performance of BASE.128 were compared to that of the antibiotic solution currently used [...]
Optimization of cardiovascular tissue decontamination and rinsing with BASE.128 and BASE
Anno: 2011, EATB Autori: Terzi A.; Buzzi M.; Guarino A.; Dainese L.; Vasuri F., D’Amato Tóthová J.; Gatto C. Abstract: We studied the optimal conditions to decontaminate and rinse cardiovascular tissues intended for transplantation [...]
Validation of standardized industrial antibiotic cocktails
Anno: 2010, Cardiovascular Tissue Bank Meeting Autori: Gatto C.; Giurgola L.; D’Amato Tóthová J. Abstract: The aim of the present study was to evaluate the performances of the industrial antibiotic cocktail BASE.128 as compared [...]
Elimination of antibiotic carry-over from tissues decontaminated with Base.128
Anno: 2010, EATB Autori: Gatto C.; Beccaro M.; Lipartiti M.; D’Amato Tóthová J. Abstract: Decontamination of tissue allografts in antibiotic cocktails can lead to the antibiotic carry-over effect, which in turn can result in [...]
Fate of antibiotics after tissue decontamination. Study on heart valves, pericardium, bone and skin
Anno: 2010, BATB Autori: D’Amato Tóthová J.; Gatto C.; Cavallaro D.; Beccaro M.; Lipartiti M. Abstract: Elimination of residual antibiotics from allograft/human tissues intended for transplantation after decontamination is paramount to ensure tissue quality and [...]
Effects of tissue, time and temperature on decontamination efficacy of Base.128
Anno: 2010, BATB Autori: D’Amato Tóthová J.; Gatto C.; Beccaro M.; Candeo L.; Bortoluzzi S.; Lipartiti M. Introduction: Decontamination is a crucial step in allograft processing. Tissue banks have established their own decontamination [...]
Comparison among the medical devices BASE.128, BASE, CRYO.ON and the solutions currently used in two Italian cardiovascular tissue banks
Anno: 2010, EATB Autori: Gatto C.; Marchiani A.; Ruzza P.; Beccaro M.; D’Amato Tóthová, J. Abstract: We evaluated the performances of the HTP medical devices in comparison with solutions currently used by the Cardiovascular [...]
Fate of antibiotics after the tissue decontamination phase: Study on pig heart valves
Anno: 2009, EATB Autori: D’Amato Tóthová J.; Gatto C.; Cavallaro D.; Beccaro M.; Lipartiti M. Abstract: Elimination of residual antibiotics from allograft/human tissues intended for transplantation after decontamination is paramount to ensure tissue quality [...]
Effects of temperature on decontamination efficacy of BASE.128 by in vitro Time-Kill studies
Anno: 2009, EATB Autori: D’Amato Tóthová J.; Gatto C.; Beccaro M.; Candeo L.; Bortoluzzi S.; Lipartiti M. Abstract: Decontamination is a crucial step in allograft processing. Tissue banks have established decontamination procedures using different [...]

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BASE

BASE è una soluzione di lavaggio capace di rimuovere gli antibiotici da vari tessuti umani destinati al trapianto (cardiovascolare, muscoloscheletrico, osteotendineo, cute e membrana amniotic [...]
Category: Banche dei tessutiSoluzioni per il lavaggio

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Packaging	Bottiglia
Items	1
Volume	250 ml, 500 ml

Cos’è BASE.128?

Destinazione d’uso

Caratteristiche

Documenti tecnici

Certificato CE 335.83 KB 1059 downloads

Documento Tecnico - BAS 005-00 493.39 KB 274 downloads

Documento Tecnico - BAS 006-00 485.45 KB 242 downloads

Pubblicazioni e presentazioni

Prodotti correlati

Richiedi informazioni su BASE.128

Richiedi informazioni su BASE.128

Informazioni aggiuntive

Prodotti correlati

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Ophthalmic Surgery

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